The effect of taurine or betaine pretreatment on hepatotoxicity and prooxidant status induced by lipopolysaccharide treatment in the liver of rats

Balkan J., Parildar F., Dogru-Abbasoglu S., Aykac-Toker G., Uysal M.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.17, sa.9, ss.917-921, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 9
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1097/00042737-200509000-00006
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.917-921
  • Anahtar Kelimeler: betaine, lipopolysaccharide, liver, oxidative stress, rat, taurine, OXIDATIVE STRESS, CARBON-TETRACHLORIDE, LIPID-PEROXIDATION, ETHANOL, GLUTATHIONE, INJURY, PROTECTION, OSMOLYTE, ACID
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background Taurine or betaine have been reported to have antioxidative potential and inhibit Kupffer cell activation. These effects may play an important role in their hepatoprotective effects. Therefore, they may also have protective effects in lipopolysaccharide hepatotoxicity by both inhibiting Kupffer cell activation and behaving as antioxidants.