Early Degeneration of Extracellular Matrix Used for Aortic Reconstruction During the Norwood Operation


Erek E., Aydin S. , Suzan D., Yildiz O., Demir I. H. , Odemis E.

ANNALS OF THORACIC SURGERY, cilt.101, ss.758-760, 2016 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 101 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.athoracsur.2015.04.051
  • Dergi Adı: ANNALS OF THORACIC SURGERY
  • Sayfa Sayısı: ss.758-760

Özet

The use of prosthetic patch material is often required during the surgical reconstruction of complex congenital cardiac malformations. Decellularized porcine small intestinal submucosa, a type of extracellular matrix, was recently introduced as a patch for cardiac and vascular tissue repair. Extracellular matrix was used for aortic reconstruction during the Norwood procedure in 8 consecutive neonates with hypoplastic left heart syndrome. Rapid degeneration or aneurysm formation developed in 3 of these patients who came to secondstage surgery. Extracellular matrix should be used cautiously for aortic reconstruction in infants until additional reports from other centers provide confirmation of its safety. (C) 2016 by The Society of Thoracic Surgeons