Vitamin A deficiency in patients with common variable immunodeficiency

Kilic S., Kezer E., Ilcol Y., Yakut T., Aydin S., Ulus İ. H.

JOURNAL OF CLINICAL IMMUNOLOGY, vol.25, no.3, pp.275-280, 2005 (SCI-Expanded, Scopus) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1007/s10875-005-4090-6
  • Journal Name: JOURNAL OF CLINICAL IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.275-280
  • Keywords: vitamin A, common variable immunodeficiency, cytokine, neopterin, RETINOL, SERUM
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Vitamin A, a naturally occuring antioxidant micronutrient, has immunomodulating effect in patients with immunodeficiency, including an influence on cytokine production and lymphocyte growth and functions. Vitamin A deficiency is associated with a shift from type 2 cytokines to predominantly type I cytokines. The aims of this study were to determine Vitamin A status in Common variable immunodeficiency (CVID) patients and the relationship between Vitamin A status and cytokines production.