Tetra vs. octa-How it affects the photophysical, photochemical, physicochemical and biological properties of mercaptophenol-substituted Zn phthalocyanines

TOPKAYA TAŞKIRAN, DERYA; Aydin, Derya; Ben Aziza, Haifa; ŞAHİN, ZEYNEL; Isci, Umit; Durand, Denis; Tazebay, Uygar; Gary-Bobo, Magali; DUMOULIN , FABIENNE

doi:10.1142/s1088424622500584

Tetra vs. octa-How it affects the photophysical, photochemical, physicochemical and biological properties of mercaptophenol-substituted Zn phthalocyanines

TOPKAYA TAŞKIRAN D., Aydin D., Ben Aziza H., ŞAHİN Z., Isci U., Durand D., ...Daha Fazla

JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, cilt.26, sa.11, ss.701-707, 2022 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 26 Sayı: 11
Basım Tarihi: 2022
Doi Numarası: 10.1142/s1088424622500584
Dergi Adı: JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica
Sayfa Sayıları: ss.701-707
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Zn phthalocyanines tetra- and octa- substituted in peripheral positions by mercaptophenol moieties were prepared. Photophysical, photochemical, physicochemical and biological properties relevant from a photodynamic therapy point of view have been determined, showing that the tetra-substituted derivatives have better potential, confirmed by in vitro tests performed on MCF-7 cells that induced significant cell death without showing dark toxicity.