Atıf İçin Kopyala
Bayoglu I. V., Kucukzeybek B. B., Kucukzeybek Y., Varol U., Yildiz İ., Alacacioglu A., ...Daha Fazla
BIOMEDICINE & PHARMACOTHERAPY, cilt.70, ss.190-195, 2015 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
70
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Basım Tarihi:
2015
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Doi Numarası:
10.1016/j.biopha.2015.01.019
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Dergi Adı:
BIOMEDICINE & PHARMACOTHERAPY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.190-195
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Anahtar Kelimeler:
Mesothelin, Cell surface proteins, Breast cancer, Her-2/Neu positive, Triple negative, Cell survival/proliferation, EPITHELIAL OVARIAN-CARCINOMA, PANCREATIC-CANCER, MONOCLONAL-ANTIBODY, CELL-PROLIFERATION, SEROUS CARCINOMA, GASTRIC-CANCER, SURVIVAL, TARGET, OVEREXPRESSION, IMMUNOTHERAPY
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Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli:
Hayır
Özet
Purpose: Mesothelin is a cell surface glycoprotein that is overexpressed in various malignancies. Recent studies have revealed that mesothelin plays an oncogenic role in tumor growth and drug resistance through the Wnt/NF-kappa B/PI3K/Akt signaling pathways. Herein, the expression of mesothelin in HER2-positive and triple-negative breast cancer (TNBC) has been correlated with prognosis.