The relationship between antioxidant enzymes and bladder cancer

Arikan S., Akcay T., KONUKOĞLU D., Obek C., Kural A. R.

NEOPLASMA, vol.52, no.4, pp.314-317, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 4
  • Publication Date: 2005
  • Title of Journal : NEOPLASMA
  • Page Numbers: pp.314-317


Carcinogenesis proceeds through at least three distinct stages - initiation, promotion and progression. Free radicals play an important role in the multistep complex course of carcinogenesis. Urinary bladder has been recognized as a target organ for many carcinogens, including benzidine, beta-napthylamine, 2 napthylamine, 4-aminobiphenyl. Antioxidants have been shown to inhibit both initiation and promotion in carcinogenesis.