High frequency of kidney and urinary tract anomalies in asymptomatic first-degree relatives of patients with CAKUT

BULUM AKBULUT B. , Ozcakar Z. B. , Ustuner E., Dusunceli E., Kavaz A., Duman D., ...More

PEDIATRIC NEPHROLOGY, vol.28, no.11, pp.2143-2147, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 11
  • Publication Date: 2013
  • Doi Number: 10.1007/s00467-013-2530-8
  • Title of Journal : PEDIATRIC NEPHROLOGY
  • Page Numbers: pp.2143-2147
  • Keywords: CAKUT, Familial clustering, First-degree relatives, Kidney and urinary tract anomalies, Renal ultrasound, CONGENITAL-ANOMALIES, RENAL ANOMALIES, MUTATIONS, CHILDREN, MALFORMATIONS, DUPLICATION, POPULATION, FAMILY, GENES, RET


Congenital anomalies of the kidney and urinary tract (CAKUT) commonly cause chronic kidney disease in children. While most CAKUT cases are sporadic, observed familial clustering suggests that the pathogenesis is influenced by genetic factors.