Prediction of cyclosporine A blood levels: an application of the adaptive-network-based fuzzy inference system (ANFIS) in assisting drug therapy

Goeren, Sezer; Karahoca, Adem; Onat, FILIZ; Goeren, M.

doi:10.1007/s00228-008-0490-x

Prediction of cyclosporine A blood levels: an application of the adaptive-network-based fuzzy inference system (ANFIS) in assisting drug therapy

Goeren S., Karahoca A., Onat F. , Goeren M. Z.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, vol.64, no.8, pp.807-814, 2008 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 64 Issue: 8
Publication Date: 2008
Doi Number: 10.1007/s00228-008-0490-x
Title of Journal : EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Page Numbers: pp.807-814
Keywords: adaptive-network-based fuzzy inference system, cyclosporine A, data mining, fuzzy modeling, therapeutic drug monitoring, RENAL-TRANSPLANT PATIENTS, NUCLEAR RECEPTOR, IDENTIFICATION, RECIPIENTS, 2-HOUR, TROUGH, CYP3A, C-2

Abstract

Objective Therapeutic drug monitoring (TDM) is a procedure in which the levels of drugs are assayed in various body fluids with the aim of individualizing the dose of critical drugs, such as cyclosporine A. Cyclosporine A assays are performed in blood.