Good laboratory practice for PGT-M: Turkish Society of Reproductive Medicine guidelines

Unsal, Evrim; Aktuna, Suleyman; Arda, Berna; Balaban, Basak; Baltaci, Volkan; Bayram, Asina; Bozdag, Gurkan; Candan, Zafer; Cetinkaya, Murat; Ceylaner, Serdar; Findikli, Necati; GÖKSEVER ÇELİK, HALE; Halicigil, Cihan; Kahraman, Semra; Kayacaglayan, Metin; Keles, Ipek; Kurtoglu, Ayse; Mutlu, Aylin; Ozgon, Gulay; Sukur, Yavuz; Tufekci, Mehmet; Yakin, Kayhan; Yelke, Hakan; Yildiz, Sule; Ata, Baris

doi:10.1016/j.rbmo.2024.104378

Good laboratory practice for PGT-M: Turkish Society of Reproductive Medicine guidelines

Atıf İçin Kopyala

Unsal E., Aktuna S., Arda B., Balaban B., Baltaci V., Bayram A., ...Daha Fazla

Reproductive BioMedicine Online, cilt.49, sa.6, 2024 (SCI-Expanded)

Yayın Türü: Makale / Derleme
Cilt numarası: 49 Sayı: 6
Basım Tarihi: 2024
Doi Numarası: 10.1016/j.rbmo.2024.104378
Dergi Adı: Reproductive BioMedicine Online
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, MEDLINE
Anahtar Kelimeler: Aneuploidy, Assisted reproductive technology, Embryo biopsy, Embryo vitrification, Monogenic diseases, Preimplantation genetic testing, Translocation, Tubing
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

This guideline was prepared by the Turkish Society of Reproductive Medicine to define the conditions and requirements for an outsourced preimplantation genetic testing (PGT) programme in line with the experience and needs of practitioners. This guideline is intended to be a reference document for assisted reproductive technology centres, genetic diagnosis centres, non-governmental organizations working on reproductive health, legal experts, consultants working on laboratory accreditation, academicians specializing in ethical issues, and policy makers. The Consortium aims to provide recommendations addressing the challenges of genetic testing, especially PGT for monogenic diseases (PGT-M) due to the high rate of consanguineous marriage in Turkey. For this purpose, this summary document specifically includes challenges and recommendations regarding PGT-M practice, and aims to identify and aid in prevention of errors leading to misdiagnosis. The recommendations can be modified to fit other locations.