Utility of the serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia

AVCU G., Karapinar D. Y., Akinci A. B., Sivis Z. O., Sahin A., Bal Z. S., ...Daha Fazla

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, cilt.54, ss.8-12, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.ijid.2016.10.027
  • Dergi Adı: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.8-12
  • Anahtar Kelimeler: Galactomannan, Aspergillosis, True-positive, False-positive, Children, Acute lymphoblastic leukemia, CELL TRANSPLANT RECIPIENTS, FUNGAL-INFECTIONS, PEDIATRIC-PATIENTS, CANCER, ANTIGENEMIA, REACTIVITY
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objectives: Invasive aspergillosis (IA) is an important cause of mortality and morbidity in children with hematological malignancies. The monitoring of serum galactomannan (GM) antigen is considered useful in the diagnosis of IA. The aim of this study was to determine the utility of serum GM monitoring in the early diagnosis of IA and the role of positive antigenemia in the management of children with acute lymphoblastic leukemia (ALL).