Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect


Cinar B. M. , Ozkoc G., Bolat F., Karaeminogullari O., Sezgin N. , Tandogan R. N.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, vol.23, no.5, pp.1410-1418, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1007/s00167-014-2955-z
  • Title of Journal : KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
  • Page Numbers: pp.1410-1418

Abstract

The aim of this experimental study was to evaluate the effect of intra-articular application of zoledronic acid (ZA) on joint cartilage and synovial tissue following induction of knee osteoarthritis (OA) in a rat model.