Akademik Veri Yönetim Sistemi
EACME Annual Conference, Zürich, İsviçre, 11 - 13 Eylül 2025, ss.60, (Özet Bildiri)
EACME European
Association Centres of Medical Ethics Annual Conference, Zurich 2025 Sept.
11-13
Oral Paper Abstract Conference
“Reimagining the Three Rs in the Era of One Health: A
Qualitative Research on Early Career Science Researchers”
Yesim Isil Ulman, PhD *,
Gulsah Baskavak, PhD **, Gamze Kaya, MSc ***, Kaan Bicici, MSc ****
* Acibadem Unv., Sch. of Medicine, Dept. of History of Medicine &
Ethics, COST Action IMPROVE
** Acibadem Unv., Faculty of Humanities, Dept. of Sociology
*** Acibadem Univ. Bioethics MSc. Program
**** Acibadem Unv Biophysics MSc
Program
The progress of science is needed for the
health of humans and animals, environmental sustainability, and the well-being
of society. Laboratory animals are crucial for scientific studies, contributing
to educational and scientific advancements. Over the past decade, as the One
Health concept has gained traction in policy, practice, and research, this
holistic perspective has required a reevaluation of traditional research
paradigms, including the application of the 3 Rs (Replacement, Reduction,
Refinement). Decisions on biomedical studies involving animals should be made
by considering the welfare of the animals used, and they should be based on
scientific knowledge and professional competence. This study aims to explore
how the 3 Rs advocate for animal research and how the One Health approach
applies to studies involving laboratory animals, while also investigating
researchers' awareness and attitudes, particularly their recognition of animals
as living and sentient beings. It investigates the values they invoke to
justify research and experimentation on animals (Values) and examines
their knowledge of alternative methods that could replace animal use (Replacement).
Additionally, it seeks to understand the challenges they face in determining,
calculating, and minimizing the number of animals in their studies (Reduction),
as well as their perspectives on ensuring the welfare of animals housed in
laboratory conditions (Refinement). The research further delves into
their experiences with the ethical approval process, from project preparation
to submission and evaluation by Ethics Committees (Ethical Process).
Finally, it examines how researchers perceive the interconnections between
human, animal, and environmental health, and how this perspective shapes their
research practices (One Health). This qualitative study will employ
in-depth, semi-structured interviews with early career science researchers,
complemented by participant observations during laboratory work. The collected
data will be systematically analyzed using qualitative analysis software. This
study explores the awareness, opinions, and experiences of researchers
regarding the 3 Rs & One Health. By critically examining harm-benefit analysis
through ethical responsibility from an interdisciplinary perspective, this
study aims to enhance practices in animal research and welfare by incorporating
bioethical principles that uphold respect for biodiversity, the biosphere, and
the concepts of One Health
Key Words: Ethics, Medicine, Animal Experimentation, One Health, Qualitative Research,
Early Career Scientist