Atıf İçin Kopyala
Dayanc B. E., Bansal S., Gure A. O., Gollnick S. O., Repasky E. A.
INTERNATIONAL JOURNAL OF HYPERTHERMIA, cilt.29, sa.5, ss.480-490, 2013 (SCI-Expanded)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
29
Sayı:
5
-
Basım Tarihi:
2013
-
Doi Numarası:
10.3109/02656736.2013.821526
-
Dergi Adı:
INTERNATIONAL JOURNAL OF HYPERTHERMIA
-
Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
-
Sayfa Sayıları:
ss.480-490
-
Anahtar Kelimeler:
Cytotoxicity, fever-range hyperthermia, HSF-1, MICA, Natural killer cells, NKG2D, CLASS-I MOLECULES, SHOCK FACTOR-I, NKG2D LIGANDS, CHAIN-A, T-LYMPHOCYTES, EPITHELIAL-CELLS, TRANSCRIPTIONAL REGULATION, INHIBITORY RECEPTORS, GENE-TRANSCRIPTION, NK CELLS
-
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli:
Hayır
Özet
Purpose: Previously we showed that mild thermal stress increased natural killer (NK) cell-mediated tumour cytotoxicity and that this could be blocked by anti-NKG2D or anti-MICA (major histolocompatability complex (MHC) class I related chain A) antibodies. Here, we investigated the role of the transcription factor heat shock factor 1 (HSF1) in thermal regulation of MICA expression in tumour cells in vitro and in vivo.