Risk of symptomatic radiation necrosis in patients treated with stereotactic radiosurgery for brain metastases.

Sayan M., Şahin B., Mustafayev T., Kefelioğlu E., Vergalasova I., Gupta A., ...Daha Fazla

Neurocirugia (Asturias, Spain), cilt.32, ss.261-267, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.neucir.2020.08.009
  • Dergi Adı: Neurocirugia (Asturias, Spain)
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, DIALNET
  • Sayfa Sayıları: ss.261-267
  • Anahtar Kelimeler: Brain metastases, Radiation necrosis, Stereotactic radiosurgery, Whole brain radiation therapy, GAMMA-KNIFE RADIOSURGERY, SINGLE-FRACTION, COMPLICATIONS, RADIONECROSIS, THERAPY, EPIDEMIOLOGY, PROGRESSION, DAMAGE, MODEL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Introduction: Stereotactic radiosurgery (SRS) is a treatment option in the initial management of patients with brain metastases. While its efficacy has been demonstrated in several prior studies, treatment-related complications, particularly symptomatic radiation necrosis (RN), remains as an obstacle for wider implementation of this treatment modality. We thus examined risk factors associated with the development of symptomatic RN in patients treated with SRS for brain metastases.