Heme Oxygenase 1-Generated Carbon Monoxide and Biliverdin Attenuate the Course of Experimental Necrotizing Pancreatitis

Nuhn P., Mitkus T., Ceyhan G. , Kuenzli B. M. , Bergmann F., Fischer L., ...More

PANCREAS, vol.42, no.2, pp.265-271, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1097/mpa.0b013e318264cc8b
  • Title of Journal : PANCREAS
  • Page Numbers: pp.265-271


Objective: The cytoprotective enzyme heme oxygenase 1 (HO-1) is highly up-regulated in acute pancreatitis (AP). In this study, we tested its metabolites as potential therapeutic agents for AP in rats.