ASIAN JOURNAL OF SURGERY, vol.44, no.6, pp.841-847, 2021 (SCI-Expanded)
Article / Article
ASIAN JOURNAL OF SURGERY
Science Citation Index Expanded (SCI-EXPANDED)
Extramural vascular invasion (EMVI), Magnetic resonance imaging (MRI), Neoadjuvant chemoradiotherapy, Outcome, Rectal cancer, Survival, CIRCUMFERENTIAL MARGIN INVOLVEMENT, VENOUS INVASION, PROGNOSTIC-SIGNIFICANCE, TUMOR RESPONSE, PREOPERATIVE CHEMORADIOTHERAPY, RESECTION MARGIN, LOCAL RECURRENCE, MRI, METASTASIS, SURVIVAL
Acibadem Mehmet Ali Aydinlar University Affiliated:
Background: In rectal cancer, extramural vascular invasion (EMVI) is the presence of tumour cells in blood vessels outside the muscular layer, which is associated with poor prognosis. Regression of EMVI on MRI following neoadjuvant chemoradiotherapy or its persistence may have prognostic implications. Methods: This retrospective study included 52 patients with rectal cancer who underwent total mesorectal excision following long-course neoadjuvant chemoradiotherapy (CRT). EMVI assessments were done on previous pelvic MRIs obtained before neoadjuvant CRT and eight weeks after the completion of neoadjuvant chemoradiotherapy in initially EMVI positive cases.