The role of bcl-2 family of genes during kindling

AKÇALI K. C., Sahiner M., Sahiner T.

EPILEPSIA, cilt.46, sa.2, ss.217-223, 2005 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.0013-9580.2005.13904.x
  • Dergi Adı: EPILEPSIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.217-223
  • Anahtar Kelimeler: apoptosis, kindling, bcl-2 family of genes, epilepsy, rat, TEMPORAL-LOBE EPILEPSY, INDUCED NEURONAL DAMAGE, STATUS EPILEPTICUS, KAINIC ACID, CELL-DEATH, ELECTRICAL STIMULATION, LIMBIC SEIZURES, RAT, APOPTOSIS, BAX
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Purpose: Several experimental models of human temporal lobe epilepsy have shown that apoptotic death of neurons is an important part of this degenerative disease. However, the role of apoptotic regulators is not clear during the epileptogenesis. Therefore we investigated the expression pattern of bcl-2 family of genes during the formation of kindling model of epilepsy in rats.