The role of bcl-2 family of genes during kindling

Akcali K., Sahiner M. , Sahiner T.

EPILEPSIA, vol.46, no.2, pp.217-223, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 2
  • Publication Date: 2005
  • Doi Number: 10.1111/j.0013-9580.2005.13904.x
  • Title of Journal : EPILEPSIA
  • Page Numbers: pp.217-223


Purpose: Several experimental models of human temporal lobe epilepsy have shown that apoptotic death of neurons is an important part of this degenerative disease. However, the role of apoptotic regulators is not clear during the epileptogenesis. Therefore we investigated the expression pattern of bcl-2 family of genes during the formation of kindling model of epilepsy in rats.