Atıf İçin Kopyala
Aksel G., Çorbacıoğlu Ş. K., İslam M. M., Şener A., Karaarslan F. N., Satıcı M. O., ...Daha Fazla
Turkish Journal of Emergency Medicine, cilt.24, sa.4, ss.185-205, 2024 (ESCI)
-
Yayın Türü:
Makale / Tam Makale
-
Cilt numarası:
24
Sayı:
4
-
Basım Tarihi:
2024
-
Doi Numarası:
10.4103/tjem.tjem_164_24
-
Dergi Adı:
Turkish Journal of Emergency Medicine
-
Derginin Tarandığı İndeksler:
Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
-
Sayfa Sayıları:
ss.185-205
-
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli:
Evet
Özet
Abstract
The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding. Despite its potential benefits, the use of TXA in emergency settings must be carefully evaluated due to its associated risks, including venous thromboembolism. This policy aimed to offer evidence-based recommendations on the indications and contraindications of TXA in different clinical scenarios encountered in the emergency departments. The guidelines were developed using the “Grading of Recommendations, Assessment, Development, and Evaluations” approach, incorporating systematic literature reviews, and expert consensus from the EMAT Research Committee. This document focuses on critical clinical questions regarding the efficacy and safety of TXA in situations such as gastrointestinal bleeding, multitrauma, traumatic brain injury, nontraumatic intracranial hemorrhage, hemoptysis, and epistaxis. By addressing these issues, the policy seeks to assist emergency physicians in making informed decisions about the use of TXA, ultimately aiming to improve the patient outcomes.