Biochemical changes representing oxidative stress on brain tissue due to intraabdominal hypertension in a rat model


Karabekir H. S. , Guzey F. K. , Balci C., Guvenc Y., Onur E., Akbulut G., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.3, no.3, pp.215-222, 2007 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 3
  • Publication Date: 2007
  • Title of Journal : ARCHIVES OF MEDICAL SCIENCE
  • Page Numbers: pp.215-222

Abstract

Introduction: Intraabdominal hypertension affects the central nervous system in addition to respiratory, renal and cardiovascular systems. This effect that, investigated in detail by clinical and experimental studies, is due to the increase of intracranial pressure and decrease of cerebral perfusion pressure caused by the increase of intrathoracic pressure and increase of pressure of great veins. However, no study has been found on biochemical changes on central nervous tissue due to intraabdomial hypertension.