Biochemical changes representing oxidative stress on brain tissue due to intraabdominal hypertension in a rat model

Karabekir H. S. , Guzey F. K. , Balci C., Guvenc Y., Onur E., Akbulut G., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.3, no.3, pp.215-222, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 3
  • Publication Date: 2007
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.215-222
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Introduction: Intraabdominal hypertension affects the central nervous system in addition to respiratory, renal and cardiovascular systems. This effect that, investigated in detail by clinical and experimental studies, is due to the increase of intracranial pressure and decrease of cerebral perfusion pressure caused by the increase of intrathoracic pressure and increase of pressure of great veins. However, no study has been found on biochemical changes on central nervous tissue due to intraabdomial hypertension.