LUNG, vol.187, no.2, pp.75-81, 2009 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED)
Sleep apnea, Leptin, Insulin resistance, Continuous positive airway pressure, Lipid, POSITIVE AIRWAY PRESSURE, METABOLIC SYNDROME, VISCERAL OBESITY, SENSITIVITY, DISEASE, FAT, ASSOCIATION, SEVERITY, GENDER, ADULTS
Acibadem Mehmet Ali Aydinlar University Affiliated:
Background Obstructive sleep apnea has been linked with metabolic syndrome characterized by dyslipidemia, dyscoagulation, hypertension, and diabetes mellitus type 2 and their cardiovascular consequences. This study was designed to determine the effects of 8 weeks of therapy with continuous positive airway pressure (CPAP) on insulin resistance, glucose, and lipid profile, and the relationship between leptin and insulin-resistance parameters in patients with moderate-to-severe obstructive sleep apnea.