High GRP78 levels in Covid-19 infection: A case-control study

Sabirli R., KÖSELER A., Goren T., TÜRKÇÜER İ., KURT Ö.

LIFE SCIENCES, cilt.265, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 265
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.lfs.2020.118781
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Endoplasmic reticulum stress, GRP78, Covid-19 infection, Pneumonia, ENDOPLASMIC-RETICULUM STRESS, CORONAVIRUS, PROTEIN, SEVERITY
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Introduction: Covid-19 infection was declared a global pandemic by WHO on March 11, 2020. GRP78 protein is known to be involved in the intrusion of numerous viruses. Our current study tries to provide some insight into the variation of GRP78 protein levels in patients with Covid-19 (-) pneumonia, Covid-19 (+) pneumonia, and CT negative Covid-19 infection in comparison to the normal population through a larger number of cases.