The Role of a Single Nucleotide Polymorphism of the Matrix Metalloproteinase-1 Gene Promoter Region in Invasion and Prognosis of Meningiomas


Efendioglu M., Basaran R., Bayrak O. F. , Isik N., Kaner T., Sahin F., ...More

TURKISH NEUROSURGERY, vol.24, no.5, pp.731-736, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.5137/1019-5149.jtn.9823-13.1
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.731-736

Abstract

AIM:The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region in meningiomas and its effect on invasion and prognosis.