Exposure to Perchlorate in Lactating Women and Its Associations With Newborn Thyroid Stimulating Hormone

UÇAL Y. , Sahin O. N. , Serdar M. A. , Blount B., Kumru P., Muhcu M., et al.

FRONTIERS IN ENDOCRINOLOGY, cilt.9, 2018 (SCI İndekslerine Giren Dergi)


Background: Perchlorate, thiocyanate, and nitrate can block iodide transport at the sodium iodide symporter (NIS) and this can subsequently lead to decreased thyroid hormone production and hypothyroidism. NIS inhibitor exposure has been shown to reduce iodide uptake and thyroid hormone levels; therefore we hypothesized that maternal NIS inhibitor exposure will influence both maternal and newborn thyroid function.