Effects of scaling and root planing and sub-antimicrobial dose doxycycline on oral and systemic biomarkers of disease in patients with both chronic periodontiti and coronary artery disease

Tueter G., Kurtis B., SERDAR M. A., Aykan T., Okyay K., Yuecel A., ...More

JOURNAL OF CLINICAL PERIODONTOLOGY, vol.34, no.8, pp.673-681, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 8
  • Publication Date: 2007
  • Doi Number: 10.1111/j.1600-051x.2007.01104.x
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.673-681
  • Keywords: adjunctive treatment, cardiovascular disease, C-reactive protein, gingival crevicular fluid/analysis, host modulation therapy, matrix metalloproteinases, periodontitis/therapy, plasma lipids, subantimicrobial dose doxycycline, C-REACTIVE PROTEIN, GINGIVAL CREVICULAR FLUID, MATRIX-METALLOPROTEINASE INHIBITOR, MYOCARDIAL-INFARCTION, INFLAMMATORY MARKERS, COLLAGENASE ACTIVITY, TREPONEMA-DENTICOLA, ADULT PERIODONTITIS, RISK, INFECTIONS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Objectives: This study evaluated the effects of scaling and root planing (SRP) +/- sub-antimicrobial dose doxycycline (SDD) on gingival crevicular fluid (GCF) levels of matrix metalloproteinase (NIMP) -1, -8, -13 and on serum levels of high-sensitivity C-reactive protein (HsCRP) and lipid fractions in patients with both chronic periodontitis (CP) and coronary artery disease (CAD).