Pancreatic Neuropathy Results in " Neural Remodeling " and Altered Pancreatic Innervation in Chronic Pancreatitis and Pancreatic Cancer

Ceyhan G., Demir I. E., Rauch U., Bergmann F., Mueller M. W., Buechler M. W., ...Daha Fazla

AMERICAN JOURNAL OF GASTROENTEROLOGY, cilt.104, sa.10, ss.2555-2565, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 10
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1038/ajg.2009.380
  • Dergi Adı: AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2555-2565
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

OBJECTIVES: Chronic pancreatitis (CP) and pancreatic cancer (PCa) are characterized by intrapancreatic neuropathic alterations, including increased neural density and hypertrophy, pancreatic neuritis and neural invasion (NI) by cancer cells in PCa. The aim of this study was to identify the influence of these neuropathic changes on the quality of pancreatic innervation, intrapancreatic glia, and visceral pain.