Pancreatic Neuropathy Results in " Neural Remodeling " and Altered Pancreatic Innervation in Chronic Pancreatitis and Pancreatic Cancer


Ceyhan G. , Demir I. E. , Rauch U., Bergmann F., Mueller M. W. , Buechler M. W. , ...Daha Fazla

AMERICAN JOURNAL OF GASTROENTEROLOGY, cilt.104, ss.2555-2565, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 104 Konu: 10
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1038/ajg.2009.380
  • Dergi Adı: AMERICAN JOURNAL OF GASTROENTEROLOGY
  • Sayfa Sayıları: ss.2555-2565

Özet

OBJECTIVES: Chronic pancreatitis (CP) and pancreatic cancer (PCa) are characterized by intrapancreatic neuropathic alterations, including increased neural density and hypertrophy, pancreatic neuritis and neural invasion (NI) by cancer cells in PCa. The aim of this study was to identify the influence of these neuropathic changes on the quality of pancreatic innervation, intrapancreatic glia, and visceral pain.