JOURNAL OF MEDICAL GENETICS, vol.51, no.7, pp.455-459, 2014 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF MEDICAL GENETICS
Developmental, Genetics, Mutation rate, Early post-zygotic, Mosaicism, PRIMER DESIGN, GENOME, MOSAICISM, PROGRAM, RATES
Background Human de novo single-nucleotide variation (SNV) rate is estimated to range between 0.82-1.70x10(-8) mutations per base per generation. However, contribution of early postzygotic mutations to the overall human de novo SNV rate is unknown.