Diagnostic Accuracy of a Confocal Laser Endomicroscope for In Vivo Differentiation Between Normal Injured And Tumor Tissue During Fluorescein-Guided Glioma Resection: Laboratory Investigation

Belykh, Evgenii; Miller, Eric; Patel, Arpan; Yazdanabadi, Mohammedhassan; Martirosyan, Nikolay; Yagmurlu, Kaan; Bozkurt, BARAN; Byvaltsev, Vadim; Eschbacher, Jennifer; Nakaji, Peter; Preul, Mark

doi:10.1016/j.wneu.2018.04.048

Diagnostic Accuracy of a Confocal Laser Endomicroscope for In Vivo Differentiation Between Normal Injured And Tumor Tissue During Fluorescein-Guided Glioma Resection: Laboratory Investigation

Atıf İçin Kopyala

Belykh E., Miller E. J. , Patel A. A. , Yazdanabadi M. L. , Martirosyan N. L. , Yagmurlu K., ...Daha Fazla

WORLD NEUROSURGERY, cilt.115, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 115
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.wneu.2018.04.048
Dergi Adı: WORLD NEUROSURGERY

Özet

OBJECTIVE: Glioma resection with fluorescein sodium (FNa) guidance has a potential drawback of nonspecific leakage of FNa from nontumor areas with a compromised bloode-brain barrier. We investigated the diagnostic accuracy of in vivo confocal laser endomicroscopy (CLE) after FNa administration to differentiate normal brain, injured normal brain, and tumor tissue in an animal glioma model.