Importance of MutL homologue MLH1 and MutS homologue MSH2 expression in Turkish patients with sporadic colorectal cancer

ERDAMAR ÇETİN A. S., Ucaryilmaz E., Demir G., Karahasanoglu T., Dogusoy G., DİRİCAN A., ...More

WORLD JOURNAL OF GASTROENTEROLOGY, vol.13, no.33, pp.4437-4444, 2007 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 33
  • Publication Date: 2007
  • Doi Number: 10.3748/wjg.v13.i33.4437
  • Journal Name: WORLD JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4437-4444
  • Keywords: colorectal carcinoma, MLH1, MSH2, immunohistochemistry, prognosis, DEFECTIVE MISMATCH-REPAIR, NONPOLYPOSIS COLON-CANCER, DNA-REPLICATION ERRORS, MICROSATELLITE INSTABILITY, HMSH2 PROTEINS, GENE DEFECTS, FEATURES, TUMORS, CARCINOMAS, HMLH1
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

AIM: To assess the incidence of MLH1 (the human MutL homologue) and MSH2 (the human MutS homologue) protein expression in Turkish patients with sporadic colorectal cancers and to compare their survival and clinicopathological features.