MIR376A Is a Regulator of Starvation-Induced Autophagy

Korkmaz G., Tekirdag K. A., Ozturk D. G., Kosar A., Sezerman O. U., Gozuacik D.

PLOS ONE, vol.8, no.12, 2013 (SCI-Expanded, Scopus) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 12
  • Publication Date: 2013
  • Doi Number: 10.1371/journal.pone.0082556
  • Journal Name: PLOS ONE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background: Autophagy is a vesicular trafficking process responsible for the degradation of long-lived, misfolded or abnormal proteins, as well as damaged or surplus organelles. Abnormalities of the autophagic activity may result in the accumulation of protein aggregates, organelle dysfunction, and autophagy disorders were associated with various diseases. Hence, mechanisms of autophagy regulation are under exploration.