Targeting nNOS ameliorates the severe neuropathic pain due to chronic pancreatitis


Demir I. E. , Heinrich T., Carty D. G. , Saricaoglu O. C. , Klauss S., Teller S., ...Daha Fazla

EBIOMEDICINE, cilt.46, ss.431-443, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.ebiom.2019.07.055
  • Dergi Adı: EBIOMEDICINE
  • Sayfa Sayıları: ss.431-443

Özet

Background: Pain due to pancreatic cancer/PCa or chronic pancreatitis/CP, is notoriously resistant to the strongest pain medications. Here, we aimed at deciphering the specific molecular mediators of pain at surgical-stage pancreatic disease and to discover novel translational targets.