Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease


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Akin H., Tahan G., Türe F., Eren F., Atuğ O., Tahan V., ...More

JOURNAL OF CROHNS & COLITIS, vol.5, no.1, pp.14-18, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.crohns.2010.08.008
  • Title of Journal : JOURNAL OF CROHNS & COLITIS
  • Page Numbers: pp.14-18

Abstract

Background: Increasing Increasing evidence suggests that innate immune system may have a key role in the pathogenesis of the inflammatory bowel disease (IBD). Bactericidal/permeability increasing protein (BPI) has an important role in the recognition and neutralization of gram-negative bacteria by host innate immune system. The polymorphism on BPI gene called Lys216Glu is on the suspected list of IBD pathogenesis.