Plasma malondialdehyde and erythrocyte glutathione levels in workers with cement dust-exposure silicosis


Orman A., Kahraman A., Cakar H., Ellidokuz H., Serteser M.

TOXICOLOGY, vol.207, no.1, pp.15-20, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 207 Issue: 1
  • Publication Date: 2005
  • Doi Number: 10.1016/j.tox.2004.07.021
  • Title of Journal : TOXICOLOGY
  • Page Numbers: pp.15-20
  • Keywords: cement, MDA, GSH, pulmonary function test, silisium dioxide, FREE-RADICALS, OXIDATIVE STRESS, LIPID PEROXIDES, POTENTIAL ROLE, LUNG INJURY, CELLS, GENERATION, DISEASE, BIOLOGY

Abstract

Background: Chronic exposure to cement dust has been reported to lead to several health problems. Acute and chronic exposure to quartz are associated with the provocation of an inflammatory response and triggers an extensive host defense mechanism. These inflammatory reactions result in the secretions of cytokines, eicosanoids. lytic enzymes, chemotactic factors and reactive oxygen species (ROS). This Study was designed to investigate the plasma oxidant and antioxidant status in cement plant workers.