Comparison of galactomannan, beta-D-glucan, and Aspergillus DNA in sera of high-risk adult patients with hematological malignancies for the diagnosis of invasive aspergillosis

Boluk, Gulcin; Kazak, Esra; Özkalemkaş, Fahir; Ener, Beyza; Akalin, Halis; Ağca, Harun; Okuturlar, YILDIZ; Keskin, Kursad; Burgazlioglu, Basak; Ali, Rıdvan

doi:10.3906/sag-1408-100

Comparison of galactomannan, beta-D-glucan, and Aspergillus DNA in sera of high-risk adult patients with hematological malignancies for the diagnosis of invasive aspergillosis

Atıf İçin Kopyala

Boluk G., Kazak E., Özkalemkaş F., Ener B., Akalin H., Ağca H., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.46, sa.2, ss.335-342, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 46 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.3906/sag-1408-100
Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.335-342
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Bckground/aim: Invasive aspergillosis (IA) is a fatal infection that is difficult to diagnose in immunocompromised patients. In this study, Aspergillus-specific DNA was searched using real-time PCR (RT-PCR) in serum samples. Galactomannan (GM) and/or beta-D-glucan (BDG) tests were previously performed on these samples for 70 neutropenic patients with hematological malignancy.