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AMERICAN JOURNAL OF DERMATOPATHOLOGY, vol.32, no.5, pp.492-494, 2010 (SCI-Expanded)
Psoriasiform keratosis is a recently reported unique clinicopathological entity characterized by the appearance of a solitary lesion mimicking seborrheic keratosis, actinic keratosis, or squamous cell carcinoma and histopathologic features closely resembling psoriasis. We report a 74-year-old woman presenting with a solitary, scaly lesion on the dorsum of the left arm of several months duration and histopathologic findings of psoriasiform acanthosis of the epidermis with thinning of the suprapapillary plates and intra-epidermal spongiform neutrophilic pustules, consistent with a diagnosis of psoriasiform keratosis. On additional work-up investigation, human papilloma virus type 6 was detected in the tissue examined by polymerase chain reaction technique, an association not described before.