Analysis of motor unit firing characteristics in patients with motor neuron diseases

Dikmen P., KOCASOY ORHAN E., BASLO M. B.

SOMATOSENSORY AND MOTOR RESEARCH, cilt.33, sa.1, ss.16-19, 2016 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3109/08990220.2016.1142437
  • Dergi Adı: SOMATOSENSORY AND MOTOR RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.16-19
  • Anahtar Kelimeler: ALS, firing rate variability, interpotential intervals, LMN, motor neuron diseases, motor unit firing characteristics, AMYOTROPHIC-LATERAL-SCLEROSIS, POTENTIALS, DISORDERS, FREQUENCY, CRITERIA, PATTERN, ALS
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

This study was designed to evaluate firing rate variability in patients with upper/lower motor neuron disorders. Twenty healthy subjects and 19 patients with motor neuron disorders participated in the study. Consecutive motor unit action potential pairs from extensor digitorum communis (EDC) muscle were recorded from each subject with trigger-delay line mode. Patients with motor neuron disorders (17.7 +/- 10.8 ms) showed significantly higher mean time variability of interpotential interval value than healthy volunteers (10.3 +/- 0.1 ms) (p<0.001).