Inflammatory <SUP>68</SUP>Ga FAPI-46 Uptake Mimicking a Sister Mary Joseph's Nodule in a Case of Gastric Signet Ring Cell Carcinoma
CLINICAL NUCLEAR MEDICINE, cilt.50, sa.12, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 50 Sayı: 12
- Basım Tarihi: 2025
- Doi Numarası: 10.1097/rlu.0000000000005971
- Dergi Adı: CLINICAL NUCLEAR MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
Fibroblast activation protein (FAP) is a type II transmembrane protease expressed in cancer-associated fibroblasts (CAF) that constitute a part of the tumor stroma and influence the tumor microenvironment. Although FAP is not expected to be physiologically expressed in noncancer-associated cells, it can be observed in wound healing, arthritis, atherosclerotic plaques, and fibrosis. In this case, we would like to present early-stage 68Ga FAPI-46 PET/CT inflammation findings at the trocar entry site mimicking the Sister Mary Joseph's nodule in a patient diagnosed with gastric signet ring cell carcinoma.