Relationship between the serum sCD40L level and aspirin-resistant platelet aggregation in patients with stable coronary artery disease

Pamukcu B., Oflaz H., Onur L., MİDİLLİ K., Yilmaz G., Yilmaz E., ...Daha Fazla

CIRCULATION JOURNAL, cilt.72, sa.1, ss.61-66, 2008 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1253/circj.72.61
  • Dergi Adı: CIRCULATION JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.61-66
  • Anahtar Kelimeler: arterial thrombosis, aspirin resistance, coronary artery disease, PFA-100, platelet function assays, sCD40L, SOLUBLE CD40 LIGAND, IIIA POLYMORPHISM, IN-VITRO, ACTIVATION, RISK, ENHANCEMENT, PREVENTION, EXERCISE, TRIGGERS, RELEASE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background Current evidence supports the central role of inflammation in all phases of the atherosclerotic process, including its thrombotic complications. Increased serum sCD40L may trigger platelet activation, so the aim of the present study was to determine the relation between sCD40L levels and aspirin-resistant platelet aggregation in patients with coronary atherosclerosis.