Is basal serum 17-OH progesterone a reliable parameter to predict nonclassical congenital adrenal hyperplasia in premature adrenarche?


GÖNÇ E. N., ÖZÖN Z. A., ALİKAŞİFOĞLU A., Engiz O., Bulum B., KANDEMİR N.

TURKISH JOURNAL OF PEDIATRICS, cilt.53, sa.3, ss.274-280, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 3
  • Basım Tarihi: 2011
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.274-280
  • Anahtar Kelimeler: premature adrenarche, adrenocorticotropic hormone (ACTH) stimulation test, nonclassical congenital adrenal hyperplasia, nonclassical 21 hydroxylase deficiency, 17-hydroxyprogesterone, WEIGHT HEIGHT VELOCITY, 21-HYDROXYLASE DEFICIENCY, CHILDREN, PUBARCHE, GIRLS, PREVALENCE, STANDARDS, MATURITY, DEFECTS, BIRTH
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

To determine the critical features for the diagnosis of nonclassical 21 hydroxylase deficiency (NC21OHD) without performing adrenocorticotropic hormone (ACTH) test, we studied 186 cases with premature adrenarche. Clinical and laboratory features as well as basal 17-hydroxyprogesterone (17-OHP) were analyzed to determine factors important for differentiating NC21OHD.