Is basal serum 17-OH progesterone a reliable parameter to predict nonclassical congenital adrenal hyperplasia in premature adrenarche?


GÖNÇ E. N. , ÖZÖN Z. A. , ALİKAŞİFOĞLU A., Engiz O., Bulum B. , KANDEMİR N.

TURKISH JOURNAL OF PEDIATRICS, vol.53, no.3, pp.274-280, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 3
  • Publication Date: 2011
  • Title of Journal : TURKISH JOURNAL OF PEDIATRICS
  • Page Numbers: pp.274-280

Abstract

To determine the critical features for the diagnosis of nonclassical 21 hydroxylase deficiency (NC21OHD) without performing adrenocorticotropic hormone (ACTH) test, we studied 186 cases with premature adrenarche. Clinical and laboratory features as well as basal 17-hydroxyprogesterone (17-OHP) were analyzed to determine factors important for differentiating NC21OHD.