Intraoperative magnetic resonance spectroscopy for identification of residual tumor during low-grade glioma surgery Clinical article
JOURNAL OF NEUROSURGERY, cilt.118, sa.6, ss.1191-1198, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 118 Sayı: 6
- Basım Tarihi: 2013
- Doi Numarası: 10.3171/2013.1.jns111561
- Dergi Adı: JOURNAL OF NEUROSURGERY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1191-1198
- Anahtar Kelimeler: 3-T intraoperative magnetic resonance imaging, low-grade glioma, magnetic resonance spectroscopy, oncology, MR-SPECTROSCOPY, BRAIN-TUMORS, RESECTION, DISTINCTION, EXTENT
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
Object. The authors had previously shown that 3-T intraoperative MRI (ioMRI) detects residual tumor tissue during low-grade glioma and that it helps to increase the extent of resection. In a proportion of their cases, however, the ioMRI disclosed T2-hyperintense areas at the tumor resection border after the initial resection attempt and prompted a differential diagnosis between residual tumor and nontumoral changes. To guide this differential diagnosis the authors used intraoperative long-TE single-voxel proton MR spectroscopy (ioMRS) and tested the correlation of these findings with findings from pathological examination of resected tissue.