international journal of fertility & sterility, vol.7, no.1, pp.29-34, 2013 (Peer-Reviewed Journal)
Background: This study assessed the relationship between endometrial thickness on human
chorionic gonadotropin (hCG) day and in vitro fertilization-intracytoplasmic sperm
Materials and Methods: This prospective cross-sectional study included a total of 593
women. Patients were treated with either the agonist or antagonist protocol according to the
clinician’s and patient’s preference. Endometrial thickness on the hCG day was measured
by transvaginal ultrasonography (TV USG). Patients were divided into four groups according
to endometrial lines, as follows: <7 mm (group 1), 7-10 mm (group 2), 10-14 mm
(group 3), and >14 mm (group 4).
Results: Implantation rate (IR), clinical pregnancy rate (CPR), and ongoing pregnancy
rate (OPR) were significantly lower in group 1 than the other three groups (p<0.05).
However, there was no significant difference among groups 2, 3 and 4. Although the
endometrial line in the agonist protocol was higher than in the antagonist protocol, the
difference was not statistically significant.
Conclusion: There is a correlation between endometrial thickness and CPR only in the
group 1 that is less than the other groups. IVF-ICSI outcome is negatively influenced
when the endometrial line is below 7 mm.