Effect of carvedilol on silent anthracycline-induced cardiotoxicity assessed by strain imaging: A prospective randomized controlled study with six-month follow-up

ELİTOK A., Oz F., Cizgici A. Y., Kilic L., Ciftci R., Sen F., ...More

CARDIOLOGY JOURNAL, vol.21, no.5, pp.509-515, 2014 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.5603/cj.a2013.0150
  • Journal Name: CARDIOLOGY JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.509-515
  • Keywords: strain imaging, antracycline induced cardiotoxicity, echocardiography, carvedilol, beta-blocker, CONGESTIVE-HEART-FAILURE, MYOCARDIAL DYSFUNCTION, INDUCED CARDIOMYOPATHY, PEDIATRIC-PATIENTS, DOXORUBICIN, ADRIAMYCIN, CHILDREN, THERAPY, CANCER
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background: The use of antracycline (ANT) in breast cancer has been associated with adverse cardiac events. Two-dimensional (2D) strain imaging (SI) can provide a more sensitive measure of altered left ventricular (LV) systolic function. We aimed to evaluate the preventive effect of carvedilol administration assessed by SI in a patient with breast cancer treated with ANT.