Recurrent hydatidiform mole: when to stop?

Özbaşlı E. , Takmaz Ö. , Gürkan H., Alanay Y. , Güngör M. , Dede F. S.

Clinical And Experimental Obstetrics & Gynecology, cilt.47, ss.424-426, 2020 (SCI Expanded İndekslerine Giren Dergi)

  • Cilt numarası: 47 Konu: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.31083/j.ceog.2020.03.5215
  • Dergi Adı: Clinical And Experimental Obstetrics & Gynecology
  • Sayfa Sayıları: ss.424-426


Recurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observed in RHM. The authors report a patient from Turkey with a history of seven molar pregnancies who had an aunt with similar obstetric history and NLRP7 mutations.
Key words:  Familial hydatidiform mole      NLRP7      Ovum donation      Genomic imprinting     
Submitted:  04 March 2019      Accepted:  04 June 2019      Published:  15 June 2020     
*Corresponding Author(s):  ESRA OZBASLI     E-mail: