Microbiologic, Pharmacokinetic, and Clinical Effects of Corneal Collagen Cross-Linking on Experimentally Induced Pseudomonas Keratitis in Rabbits.

Cosar C. B., Kucuk M., Celik E., Gonen T., Akyar I., SERTESER M., ...Daha Fazla

Cornea, cilt.34, sa.10, ss.1276-80, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/ico.0000000000000516
  • Dergi Adı: Cornea
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1276-80
  • Anahtar Kelimeler: Pseudomonas corneal ulcer, microbial keratitis, experimental keratitis, cross-linking, moxifloxacine, INFECTIOUS KERATITIS, PACK-CXL, RIBOFLAVIN, EFFICACY, PERMEABILITY, PENETRATION, BACTERIAL, THERAPY
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Purpose: To determine the effects of corneal collagen cross-linking (CXL) on the penetration of topical 0.5% moxifloxacin, on the number of colony-forming units (CFUs) in the cornea, and on the clinical course in a rabbit eye model of experimentally induced Pseudomonas aeruginosa keratitis.