VEGA-Vision: Wireless fNIRS with Spatially Resolved Short Separation Approach for Improved SNR


Yoner S. I. , Ertaş G., Akın A.

fNIRS2018, Tokyo, Japan, 5 - 08 October 2018, pp.78

  • Publication Type: Conference Paper / Summary Text
  • City: Tokyo
  • Country: Japan
  • Page Numbers: pp.78

Abstract

Recent technological trends in fNIRS hardware design focus on improving the

SNR while making the device wireless, affordable and easy to use. To address these issues,

we developed a wireless 8-channel cw-fNIRS system (VEGA-Vision) with short/far

separation detector pairs (1.5/3 cm separation). Measurements were taken from nonsmoking

and smoking individuals during a head-tilt maneuver protocol. Total hemoglobin

(TotHb) changes from resting to head down and from head down to up showed statistically

different values: deviation of delta TotHb down between non-smokers and smokers was 33.2%

(P=0.040) for the right half of brain and 35.4% (P=0.008) for the 4th channel from left end side,

meanwhile deviation of delta TotHb up between non-smokers and smokers was 30.0%

(P=0.040) for the right half of brain and 30.8% (P=0.015) for the 4th channel from left end side.

Results suggest less arterial vasodilation in smokers when compared to non-smokers.

Healthy smooth muscle cells are known to control vasodilation and vasoconstriction by

relaxation and contraction, a mechanism that is somehow impaired in smokers due to

excessive number of smooth muscle cells in the region. Thereby decreased elastic property

is caused by thickening of arterial walls (1). A study done on rats, revealed that chronic

nicotine exposure decreases cerebral blood flow (2). Vasodilation abnormalities of smokers

compared to non-smokers may be also effected by reduced cerebral blood flow, thereby less

arterial wall pressure followed by less vasodilation. We conclude that VEGA-Vision provides

a fast, accurate, affordable and easy-to-use alternative to existing designs ready to be

employed in clinical studies.