Rare association of solitary necrotic nodule of the liver with rheumatoid arthritis and systemic lupus erythematosus


Kocanali N., Kilickan F. D. B., Kirimlioglu H., Gonenc M., TÖZÜN A. N., DİNÇER A., ...Daha Fazla

HEPATOLOGY FORUM, cilt.4, sa.1, ss.37-39, 2023 (ESCI) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.14744/hf.2022.2022.0020
  • Dergi Adı: HEPATOLOGY FORUM
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.37-39
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Solitary necrotic nodule of the liver (SNNL) is a rare benign lesion with uncertain etiology characterized by a "completely necrotic core" and a hyalinized capsule containing elastin fibers (Journal of Clinical Pathology 36:1181-1183, 1983). We report herein a 26-year-old woman with a previ-ous diagnosis of rheumatoid arthritis, systemic lupus erythematosus, and Sjogren's syndrome and no history of malignancy who presented with a complaint of diarrhea of 1-year duration. In the abdominal ultrasound, mul-tiple paraaortic, portocaval, and ileal lymphadenopathies (LAPs) have been found with the largest one being 2 cm in size. The biopsy of the iliac LAP showed reactive nodular hyperplasia. An abdominal CT disclosed an inci-dental hypoechoic, heterogenous mass sized 27 x 27 mm close to segment VI of the liver. A trucut biopsy of this lesion was made, and clinicopatho-logic features of the specimen were compatible with a solitary necrotic nod-ule of the liver. Here, we discuss the diagnosis and the clinical course of this rare entity in light of current literature.