A case of lupus vulgaris successfully treated with antituberculous therapy despite negative PCR and culture
DERMATOLOGY, cilt.211, sa.3, ss.290-292, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 211 Sayı: 3
- Basım Tarihi: 2005
- Doi Numarası: 10.1159/000087027
- Dergi Adı: DERMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.290-292
- Anahtar Kelimeler: cutaneous tuberculosis, lupus vulgaris, polymerase chain reaction, CUTANEOUS LEISHMANIASIS, MYCOBACTERIAL DNA, TUBERCULOSIS
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır
Özet
A 14-year-old boy presented with a pink firm plaque with well-defined borders in the right infra-orbital skin area. On diascopy, the infiltrate exhibited a typical apple-jelly appearance. No acid-fast bacilli could be demonstrated. A polymerase chain reaction (PCR) assay did not reveal the presence of mycobacteria in a lesional biopsy sample. Culture of biopsied tissue on Loewenstein-Jensen medium was negative. Although the tuberculosis culture and PCR did not confirm tuberculosis, a diagnosis of lupus vulgaris was made considering the clinical and histopathological findings. After a 9-month antituberculous therapy, the lesion disappeared. We believe that a diagnosis of lupus vulgaris still depends more on clinical and histopathological findings than on tuberculosis culture or PCR.