Lung cancer (Amsterdam, Netherlands), vol.148, pp.48-54, 2020 (Journal Indexed in SCI Expanded)
Article / Article
Title of Journal :
Lung cancer (Amsterdam, Netherlands)
Lorlatinib, Real-world data, ALK, ROS1, CELL LUNG-CANCER, HYBRID CAPTURE, SINGLE-ARM, OPEN-LABEL, CRIZOTINIB, REARRANGEMENT, IMMUNOHISTOCHEMISTRY, MULTICENTER, CRITERIA, RET
Lorlatinib is a third-generation tyrosine-kinases inhibitor (TKI) targeting ALK/ROS1 fusions. The FDA has approved lorlatinib for TKI-pretreated ALK(+) NSCLC, while its approval for ROS1( + ) is still pending. Here we present the largest real-world data of NSCLC patients harboring ALK/ROS1 rearrangements treated with lorlatinib.