Diagnosis of Periprosthetic Infection: Recent Developments

Wasterlain A. S., Goswami K., Ghasemi S. A., PARVİZİ J.

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, cilt.102, sa.15, ss.1366-1375, 2020 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 102 Sayı: 15
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2106/jbjs.19.00598
  • Dergi Adı: JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Public Affairs Index, SportDiscus, Veterinary Science Database
  • Sayfa Sayıları: ss.1366-1375
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

There is no absolute test for the preoperative diagnosis of periprosthetic joint infection (PJI); thus, clinical practice relies on a combination of supportive tests and criteria.Novel serum and synovial tests have improved our ability to diagnose PJI. The 2018 evidence-based algorithm for PJI diagnosis provides weighted scores for serum markers, as well as synovial markers, to facilitate diagnosis when major criteria such as positive cultures or a sinus tract are not present.Culture-independent technologies such as next-generation sequencing can facilitate pathogen identification, particularly in the setting of culture-negative PJI.Despite recent developments, PJI diagnosis remains challenging and warrants further innovation.