NON-MUSCLE INVASIVE BLADDER CANCER RESISTANT TO BCG


Turker P., Turkeri L.

ARCHIVOS ESPANOLES DE UROLOGIA, cilt.66, sa.9, ss.833-840, 2013 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Konu: 9
  • Basım Tarihi: 2013
  • Dergi Adı: ARCHIVOS ESPANOLES DE UROLOGIA
  • Sayfa Sayıları: ss.833-840

Özet

Treatment options for patients with non-muscle invasive bladder cancer (NM/BC) refractory to intravesical bacillus Calmette-Guerin (BCG) therapy is reviewed in this article based on the recent published literature. Although intravesical BCG is the best bladder sparing treatment option for NM/BC to prevent recurrence and progression, about 1/3 of cases are refractory to this treatment. At this point radical cystectomy is the standard treatment of choice. If this option is not feasible, intravesical chemotherapy with docetaxel or gemcitabine, the combination of BCG and interferon (INF)-alpha or device-assisted intravesical strategies, such as mitomycin-EMDA or chemohyperthermia are some of the candidates for further treatment.