Cyclotriphosphazene, a scaffold for F-19 MRI contrast agents


Onal E., Zhang C., Davarci D., Isci U., Pilet G., Whittaker A. K. , ...Daha Fazla

TETRAHEDRON LETTERS, cilt.59, ss.521-523, 2018 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 59 Konu: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.tetlet.2017.12.032
  • Dergi Adı: TETRAHEDRON LETTERS
  • Sayfa Sayıları: ss.521-523

Özet

A cyclotriphosphazene substituted with six 3,5-bis(trifluoromethyl) benzyloxy units was designed as a novel F-19 MRI contrast agent. The resulting molecule has 36 magnetically equivalent fluorine atoms and exhibited suitable MRI properties with high imaging sensitivity, confirming the proof-of-concept as a convenient scaffold for the production of new F-19 MRI contrasts agents. (C) 2017 Elsevier Ltd. All rights reserved.